Recent publications featuring Transition's E1-I.N.T.™
New Sources of Pancreatic Beta Cells
- Nature Biotechnology 23, 857 - 861 (2005)

The Endless Possibilities of Beta Cell Regeneration
- Juvenile Diabetes Research Foundation CountDown Magazine

Researchers Make New Beta Cells Grow from Pancreatic Tissue
- Juvenile Diabetes Research Foundation Progress Report
- Nature Biotechnology 23, 857 - 861 (2005)
The Endless Possibilities of Beta Cell Regeneration
- Juvenile Diabetes Research Foundation CountDown Magazine
Researchers Make New Beta Cells Grow from Pancreatic Tissue
- Juvenile Diabetes Research Foundation Progress Report
I.N.T.™ References
Wilma L. Suarez-Pinzon et al. "Combination Therapy with Epidermal Growth Factor and Gastrin Increases beta-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice"
- Diabetes (2005) 54:2596-2601

Brand et al. "Pharmacological Treatment of Chronic Diabetes by Stimulating Pancreatic beta-Cell Regeneration with Systemic Co-Administration of EGF and Gastrin"
- Pharmacology & Toxicology (2002) 91:414-420

Rooman et al. "Combined Gastrin and Epidermal Growth Factor Treatment Induces Islet Regeneration and restores Normoglycaemia in C57B16/J Mice Treated with Alloxan" Rooman I et al.;
- Diabetologia (2004) 47:259-265

Suarez-Pinzon WL. et al. "Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet beta-Cells from Pancreatic Ductal cells and an Increase in Functional beta-Cell Mass"
- J Clin Endocrinol Metab. (2005) 90:3401-3409

Wang TC. et al. "Pancreatic Gastrin Stimulates Islet Differentiation of Transforming Growth Factor a-Induced ductular Precursor Cells"
- J of Clin Invest (Sept. 1993) 92:1349-1356

Rooman I. et al. "Gastrin Stimulates beta-Cell Neogenesis and Increase Islet Mass from Transdifferentiated but not from Normal Exocrine Pancreas Tissue"
- Diabetes (March 2002) 51:686-690

Cras-Meneur C. et al. "Epidermal Growth Factor Increases Undifferentiated Pancreatic Embryonic Cells in Vitro"
- Diabetes (July 2001) 50:1571-1579
- Diabetes (2005) 54:2596-2601
Brand et al. "Pharmacological Treatment of Chronic Diabetes by Stimulating Pancreatic beta-Cell Regeneration with Systemic Co-Administration of EGF and Gastrin"
- Pharmacology & Toxicology (2002) 91:414-420
Rooman et al. "Combined Gastrin and Epidermal Growth Factor Treatment Induces Islet Regeneration and restores Normoglycaemia in C57B16/J Mice Treated with Alloxan" Rooman I et al.;
- Diabetologia (2004) 47:259-265
Suarez-Pinzon WL. et al. "Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet beta-Cells from Pancreatic Ductal cells and an Increase in Functional beta-Cell Mass"
- J Clin Endocrinol Metab. (2005) 90:3401-3409
Wang TC. et al. "Pancreatic Gastrin Stimulates Islet Differentiation of Transforming Growth Factor a-Induced ductular Precursor Cells"
- J of Clin Invest (Sept. 1993) 92:1349-1356
Rooman I. et al. "Gastrin Stimulates beta-Cell Neogenesis and Increase Islet Mass from Transdifferentiated but not from Normal Exocrine Pancreas Tissue"
- Diabetes (March 2002) 51:686-690
Cras-Meneur C. et al. "Epidermal Growth Factor Increases Undifferentiated Pancreatic Embryonic Cells in Vitro"
- Diabetes (July 2001) 50:1571-1579